推荐文章

热门文章

title=""/

郑敏化副教授


更新时间:2010-04-19



点击浏览下一页

郑敏化女,讲师。2003获第四军医大学临床医学专业学士学位,2009获得第四军医大学发育生物学专业博士学位。从事转录因子RBP-J通过介导Notch信号调控神经细胞分化的研究。2006-2008年在中科院上海生命科学院神经科学研究所进修,开展以视网膜为模型从事神经发育研究,延续至今。现为中国神经科学学会及美国神经科学学会会员,2009年获得中国神经科学学会赛诺菲-安万特中国神经科学优秀会议论文奖。承担国家自然科学基金1项(青年项目),参与国家973课题子项目1项和国家自然科学基金项目7项。熟悉神经系统发育基本理论,掌握转基因小鼠分析的常用技术和方法。

代表性论著:

1.Zheng MH, Zhang ZF, Zhao XC, Ding YQ, Han H. The Notch signaling pathway in retinal dysplasia and retina vascular homeostasis.J. Genet. Genomics.2010; 37(In press).

2.Zheng MH, Shi M, Pei Z, Gao F, Han H, Ding YQ. The transcription factor RBP-J is essential for retinal cell differentiation and lamination.Mol. Brain.2009; 2:38.

3.Zheng MH*, Hu YY*, Fu LA, Han H.Regulation of Cancer Stem Cells by the Notch Signaling Pathway: Basic Mechanisms and Clinical Implications. a chapter ofCancer Stem Cells. Columbus F(editor in chief); NovaScience Publishers. 2010 Feb. (In publication).

4.Gao F*, Zhang Q*,Zheng MH, Liu HL, Hu YY, Zhang P, Zhang ZP, Qin HY, Feng L, Wang L,Hua Han, Gong Ju. Transcription factor RBP-J-mediated signaling represses the differentiation of neural stem cells into intermediate neural progenitors.Mol. Cell. Neurosci.2009; 40(4):442-50.

5.Zhang R, Ma LY,Zheng MH, Ren JL, Wang T, Meng YL, Zhao J, Jia LT, Yao LB, Han H, Li KZ, Yang AG. Survivin knockdown by short hairpin RNA abrogates the growth of human hepatocellular carcinoma xenografts in nude mice.Cancer Gene Ther.2010; 17(4):275-88.

6.Zhao GY, Li ZY, Zou HL, Hu ZL, Song NN,Zheng MH, Su CJ, Ding YQ. Expression of the transcription factor GATA3 in the postnatal mouse central nervous system.Neurosci Res.2008;61(4):420-8.

7.Wang JS,Qin HY,Liang J,ZhuYT,Liang L,Zheng MH,Han H. The transcriptional repression activity of KyoT2 on the Notch/RBP-J pathway is regulated by PIAS1-catalyzed SUMOylation.J. Mol. Biol.2007; 370:27-38.


上一条:张萍副教授

关闭