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冯蕾高级实验师


更新时间:2014-05-16



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冯蕾女,1975年7月3日,第四军医大学基础部医学遗传学与发育生物学教研室讲师。1998年毕业于第二军医大学,获学士学位。2005年毕业于第四军医大学医学遗传学与发育生物学教研室发育生物学专业,获硕士学位,2008年获该学科博士学位,学位论文题目转基因小鼠平台的建立、技术优化及Tie2-CreERTM转基因小鼠的构建,导师是国家杰出青年基金获得者韩骅教授。主要从事转基因小鼠的构建及研究工作。2007获国科金面上项目一项名称为:脾脏边缘带B细胞组织定位的分子机理。

近期发表主要论文:

1.冯蕾,韩骅。抗黑色素瘤嵌合抗体的构建与表达。中国免疫学杂志。2005; 21,247-250.

2.冯蕾,韩骅。人治疗性抗体的研究进展。细胞与分子免疫学杂志,2005; 21,S49-51.

3.Hongyan Qin,Dewei Du,Yangting Zhu,Junfeng Li,Lei Feng,Yingmin Liang,and Hua Han.The PcG protein HPC2 inhibits RBP-J-mediated transcription by interacting with LIM protein KyoT2, FEBS letters, 2005, 579,1220-1226.

4.孙强,黄红艳,周鹏,冯蕾,秦红,韩骅。用suc2信号肽捕获系统筛选小鼠胚胎cDNA文库基因。中国生物化学与分子生物学报,2004;20,507-512.

5.Xue-Ping Zhang,Gang Zheng,Lian Zou,Hui-Ling Liu,Li-Hong Hou,Peng Zhou,Dan-Dan Yin,Qi-Jun Zheng,Liang Liang,Su-Zhen Zhang,Lei Feng,Li-Bo Yao,An-Gang Yang,Hua Han,Jing-Yuan Chen,Notch activation promotes cell proliferation and the formationof neural stem cell-like colonies in human glioma cells,Mol Cell Biochem (2008) 307:101–108

6. Tao Fu,Ping Zhang,Lei Feng, Accelerated acute allograft rejection accompanied by enhanced T-cell proliferation and attenuated Treg function in RBP-J deficient mice. Molecular Immunology.2011(48):751–759.(Co-frist anthor)(IF:3.202)

7. Jing-Yuan Chen,Lei Feng, Hai-Long Zhang, Jun-Chang Li, Xin-Wei Yang, Xiu-Li Cao, Li Liu, Hong-Yan Qin, Ying-Min Liang, Hua Han*. Differential Regulation of Bone Marrow-Derived Endothelial Progenitor Cells and Endothelial Outgrowth Cells by the Notch Signaling Pathway.plos one. 2012,7(10): e43643 (Co-frist anthor)(IF:4.097)

8. Zhi Li,Lei Feng, Deletion of RBP-J in adult mice coincides with the onset of aortic valve degenerative diseases. Life science.(2012) 39:3837–3845(Co-frist anthor) (IF:2.56)


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