推荐文章

热门文章

title=""/

梁亮讲师


更新时间:2014-05-19



点击浏览下一页

梁亮女,1980年10月16日生,博士,第四军医大学基础部医学遗传和发育生物教研室讲师。2004毕业于第四军医大学临床医学系,2005年考取发育生物学专业硕士,2008年通过硕博连读申请答辩,攻读本专业博士。主要从事NOTCH信号途径在血管发育、肿瘤发生过程中的机理的研究。目前负责国家自然科学基金青年项目一项(项目批准号:31101054)和863课题《重大疾病小鼠模型建立和应用》子项目一项(2012AA022402)。

近期发表主要论文:

1.Liang Liang,Hong-Wei Zhang, Jie Liang, XiaoLi Niu, SuZhen Zhang, Lei Feng, YingMin Liang,Hua HanCA.KyoT3, an isoform of murine FHL1, associates with the transcription factorRBP-J and represses the RBP-J-mediated transactivation.Biochemica et Biophysica Acta.2008;1779:805-810.

2.Xue-Ping Zhang, Gang Zheng, Lian Zou, Hui-Ling Liu, Li-Hong Hou, Peng Zhou, Dan-Dan Yin, Qi-Jun Zheng,Liang Liang, Su-Zhen Zhang, Lei Feng,Li-Bo Yao, An-Gang Yang, Hua Han, Jing-Yuan Chen. Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells.Mol. Cell. Biochem.2008;307:101-108.

3.Xue-Ping Zhang, Gang Zheng, Lian Zou, Hui-Ling Liu, Li-Hong Hou, Peng Zhou, Dan-Dan Yin, Qi-Jun Zheng,Liang Liang,Su-Zhen Zhang, Lei Feng,Li-Bo Yao, An-Gang Yang, Hua Han, Jing-Yuan Chen. Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells.Mol. Cell. Biochem.2008;307:101-108.

4.Xue-Ping Zhang, Gang Zheng, Lian Zou, Hui-Ling Liu, Li-Hong Hou, Peng Zhou, Dan-Dan Yin, Qi-Jun Zheng,Liang Liang,Su-Zhen Zhang, Lei Feng,Li-Bo Yao, An-Gang Yang, Hua Han, Jing-Yuan Chen. Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells.Mol. Cell. Biochem.2008;307:101-108.

5.Junfeng Li, Jishu Wang, Xi Yang, Junlin Li, Hongyan Qin, Xiao Dong, Yangting Zhu,Liang Liang,Yingmin Liang, Hua Han.The Spen homolog Msx2-interacting nuclear target proteininteracts with the E2 ubiquitin-conjugating enzyme UbcH8.Mol. Cell. Biochem. 2006; 288:151-157.

6. Cai WX, Liang L, Wang L, Han JT, Zhu XX, Han H, Hu DH, Zhang P Inhibition of Notch signaling leads to increased intracellular ROS by up-regulating Nox4 expression in primary HUVECs.Cell Immunol. 2014;287(2):129-35.(共同第一作者)

7. Tian DM, Liang L, Zhao XC, Zheng MH, Cao XL, Qin HY, Wang CM, Liang YM, Han H. Endothelium-targeted Delta-like 1 promotes hematopoietic stem cell expansion ex vivo and engraftment in hematopoietic tissues in vivo.Stem Cell Res. 2013 ;11

(2):693-706. (共同第一作者)

8. Zhao XC, Dou GR, Wang L, Liang L, Tian DM, Cao XL, Qin HY, Wang CM, Zhang P, Han H. Inhibition of tumor angiogenesis

and tumor growth by the DSL domain of human Delta-like 1 targeted to vascular endothelial cells.Neoplasia. 2013; 15(7):815-25.

9. Hu XB, Feng F, Wang YC, Wang L, He F, Dou GR, Liang L, Zhang HW, Liang YM, Han H. Blockade of Notch signaling in tumor- bearing mice may lead to tumor regression, progression, or metastasis, depending on tumor cell types. Neoplasia. 2009 Jan;11(1):32-8.


上一条:胡昳旸讲师
下一条:秦鸿雁教授

关闭